Cluster GPCR ligand binding is enriched in the following gene classes
GeneSet DB Hit Count
Pathways - Reactome.gmt GeneSets 15
Cluster Name GeneSet Name GeneSet DB log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
AZAvsCD3-Dn in-CD3-activated GPCR ligand binding Pathways - Reactome.gmt GeneSets -3.1 0.00436 117.0 39.0 24.55
EntryvsLatency-Dn in-Resting GPCR ligand binding Pathways - Reactome.gmt GeneSets -2.0 0.02589 116.0 17.0 9.83
EntryvsLatency-Up in-Resting GPCR ligand binding Pathways - Reactome.gmt GeneSets -4.0 5.2E-4 116.0 17.0 6.59
IL7vsCD3-Dn in-IL7-activated GPCR ligand binding Pathways - Reactome.gmt GeneSets -2.6 0.01278 119.0 36.0 23.46
IL7vsCD3-Up in-IL7-activated GPCR ligand binding Pathways - Reactome.gmt GeneSets -4.0 7.5E-4 119.0 38.0 21.51
DMSOvsIL7-Up in-IL7-activated GPCR ligand binding Pathways - Reactome.gmt GeneSets -1.6 0.03255 112.0 3.0 1.07
HIVvsMockinLatency-Dn in-Mock GPCR ligand binding Pathways - Reactome.gmt GeneSets -2.1 0.00796 114.0 3.0 0.78
HIVvsMockinLatency-Up in-Mock GPCR ligand binding Pathways - Reactome.gmt GeneSets -6.4 0.0 114.0 8.0 0.94
DISUvsCD3-Up in-DISU-activated GPCR ligand binding Pathways - Reactome.gmt GeneSets -4.5 4.0E-4 118.0 39.0 21.36
DMSOvsCD3-Up in-DMSO-activated GPCR ligand binding Pathways - Reactome.gmt GeneSets -3.5 0.00186 121.0 42.0 25.86
SAHAvsCD3-Up in-SAHA-activated GPCR ligand binding Pathways - Reactome.gmt GeneSets -5.0 1.0E-4 119.0 44.0 24.27
SAHAvsIL7-Up in-SAHA-activated GPCR ligand binding Pathways - Reactome.gmt GeneSets -2.1 0.04445 111.0 15.0 8.17
DISUvsSAHA-Up in-SAHA-activated GPCR ligand binding Pathways - Reactome.gmt GeneSets -2.9 0.00846 111.0 12.0 4.82
EntryvsTCRReactivation-Up in-Entry GPCR ligand binding Pathways - Reactome.gmt GeneSets -6.1 1.0E-5 120.0 44.0 22.02
LatencyvsTCRReactivation-Up in-Resting GPCR ligand binding Pathways - Reactome.gmt GeneSets -6.6 0.0 125.0 62.0 35.57
Download list of genes
Gene expression pattern of GPCR ligand binding
Figure: : Temporal expression patterns are displayed according to the selected conditions and comparisons. Only infected conditions are displayed, during latency as gray lines or during activation according to the color code for each drug. For individual genes, select one from the table below.
List of genes
Name
6751
6753
7050
656877
657184
658080
658680
676775
677165
678272
687272
705082
716576
716771
717380
718280
737272
737656
767266
777678
787766
787783
787785
788066
788083
788087
788089
788483
798884
807052
808089
808472
808989
827182
827279
828272
836784
837272
837779
838384
848272
867380
65687750
65807678
66828351
67658382
67677650
67677651
67677652
67677653
67677655
67678249
67678250
67678251
67678252
67678253
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67678256
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67685353
67685755
67788249
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68658267
68826849
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68826853
69687849
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70837266
70837282
70906849
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70906855
70906856
70906857
71677182
71728272
71728276
71728382
71738082
71786583
71786649
71786650
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71806982
71808252
71827749
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71827754
71827755
71827756
71828082
72678284
72827249
72827250
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72827252
72848252
72848254
72848255
73658080
75787149
77674982
77675082
77675182
77675282
77675382
77767882
78776682
78807070
79807851
79807852
79807853
79888482
80688978
80697875
80776772
80787967
80797767
80806680
80827672
80847250
81827080
82767850
82767851
83656549
83678482
84656749
84656751
84827282
84837266
84837282
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87788449
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88677649
88677650
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6568826649
6568826650
6568826651
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6580767882
6586808250
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6765766765
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6765766782
6767668050
6767756582
6767756682
6767764949
6767764954
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6767765048
6767765049
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7267658250
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7269668049
7284824965
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7378837651
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7672677182
7680658249
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