Cluster Inhibition of replication initiation of damaged DNA by RB1/E2F1 is enriched in the following gene classes
| GeneSet DB | Hit Count |
|---|---|
| Pathways - Reactome.gmt GeneSets | 5 |
| Cluster Name | GeneSet Name | GeneSet DB | log(P) | Qvalue | Observed in Background | Observed in Cluster | Expected in Cluster |
|---|---|---|---|---|---|---|---|
| EntryvsLatency-Dn in-Resting | Inhibition of replication initiation of damaged DNA by RB1/E2F1 | Pathways - Reactome.gmt GeneSets | -5.6 | 2.0E-5 | 12.0 | 7.0 | 1.02 |
| DISUvsIL7-Up in-IL7-activated | Inhibition of replication initiation of damaged DNA by RB1/E2F1 | Pathways - Reactome.gmt GeneSets | -3.6 | 0.00193 | 12.0 | 3.0 | 0.3 |
| DISUvsCD3-Dn in-DISU-activated | Inhibition of replication initiation of damaged DNA by RB1/E2F1 | Pathways - Reactome.gmt GeneSets | -2.1 | 0.03791 | 12.0 | 6.0 | 2.47 |
| SAHAvsCD3-Dn in-SAHA-activated | Inhibition of replication initiation of damaged DNA by RB1/E2F1 | Pathways - Reactome.gmt GeneSets | -3.2 | 0.00385 | 12.0 | 8.0 | 2.85 |
| LatencyvsTCRReactivation-Dn in-Resting | Inhibition of replication initiation of damaged DNA by RB1/E2F1 | Pathways - Reactome.gmt GeneSets | -4.3 | 3.4E-4 | 12.0 | 11.0 | 4.36 |
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Gene expression pattern of Inhibition of replication initiation of damaged DNA by RB1/E2F1
Figure: : Temporal expression patterns are displayed according to the selected conditions and comparisons. Only infected conditions are displayed, during latency as gray lines or during activation according to the color code for each drug. For individual genes, select one from the table below.