Cluster Activation of ATR in response to replication stress is enriched in the following gene classes
GeneSet DB Hit Count
Pathways - Reactome.gmt GeneSets 10
Cluster Name GeneSet Name GeneSet DB log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
AZAvsCD3-Up in-CD3-activated Activation of ATR in response to replication stress Pathways - Reactome.gmt GeneSets -4.3 4.6E-4 37.0 19.0 8.4
AZAvsIL7-Up in-IL7-activated Activation of ATR in response to replication stress Pathways - Reactome.gmt GeneSets -4.3 5.0E-5 36.0 3.0 0.2
EntryvsLatency-Dn in-Resting Activation of ATR in response to replication stress Pathways - Reactome.gmt GeneSets -3.4028235E38 0.0 37.0 25.0 3.14
DISUvsIL7-Up in-IL7-activated Activation of ATR in response to replication stress Pathways - Reactome.gmt GeneSets -3.5 0.00228 36.0 5.0 0.9
DMSOvsIL7-Up in-IL7-activated Activation of ATR in response to replication stress Pathways - Reactome.gmt GeneSets -3.4 0.00104 36.0 3.0 0.34
DISUvsCD3-Dn in-DISU-activated Activation of ATR in response to replication stress Pathways - Reactome.gmt GeneSets -2.2 0.02971 37.0 14.0 7.61
DMSOvsCD3-Dn in-DMSO-activated Activation of ATR in response to replication stress Pathways - Reactome.gmt GeneSets -5.0 9.0E-5 37.0 21.0 9.0
SAHAvsCD3-Dn in-SAHA-activated Activation of ATR in response to replication stress Pathways - Reactome.gmt GeneSets -4.6 2.2E-4 37.0 20.0 8.77
SAHAvsIL7-Dn in-SAHA-activated Activation of ATR in response to replication stress Pathways - Reactome.gmt GeneSets -5.3 3.2E-4 36.0 11.0 2.55
LatencyvsTCRReactivation-Dn in-Resting Activation of ATR in response to replication stress Pathways - Reactome.gmt GeneSets -7.9 0.0 37.0 30.0 13.44
Download list of genes
Gene expression pattern of Activation of ATR in response to replication stress
Figure: : Temporal expression patterns are displayed according to the selected conditions and comparisons. Only infected conditions are displayed, during latency as gray lines or during activation according to the color code for each drug. For individual genes, select one from the table below.
List of genes
Name
658482
67686754
67686755
67687550
68667052
72858349
77677750
77677751
77677752
77677753
77677754
77677755
77677756
79826749
79826750
79826751
79826752
79826753
79826754
82656849
82706750
82706751
82706752
82706753
82806549
82806550
82806551
6584827380
6768675253
6772697549
6776838078
7767774948
8265684955
8265685765
8265685766
676867505365
676867505367