LITCHi
Cluster AZAvsIL7-Dn_in-IL7-activated is enriched in the following gene classes
GeneSet DB Hit Count
TF_miRNA Targets.gmt GeneSets 25
TarBase_6beta.gmt GeneSets 3
Pathways - Reactome.gmt GeneSets 5
Chromosomal Bands.gmt GeneSets 3
GO - Molecular Function.gmt GeneSets 6
GO - Cellular Component.gmt GeneSets 8
HIV Collection.gmt GeneSets 1
GO - Biological Process.gmt GeneSets 15
Cluster Name GeneSet Name GeneSet DB log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
AZAvsIL7-Dn in-IL7-activated chr1q32 Chromosomal Bands.gmt GeneSets -4.5 3.0E-5 68.0 4.0 0.35
AZAvsIL7-Dn in-IL7-activated chr2q37 Chromosomal Bands.gmt GeneSets -3.9 1.4E-4 50.0 3.0 0.26
AZAvsIL7-Dn in-IL7-activated chr12q13 Chromosomal Bands.gmt GeneSets -2.4 0.00424 126.0 3.0 0.65
AZAvsIL7-Dn in-IL7-activated CELL DEVELOPMENT GO - Biological Process.gmt GeneSets -2.2 0.01711 425.0 6.0 2.2
AZAvsIL7-Dn in-IL7-activated CELL SURFACE RECEPTOR LINKED SIGNAL TRANSDUCTION GO 0007166 GO - Biological Process.gmt GeneSets -1.7 0.03672 305.0 4.0 1.58
AZAvsIL7-Dn in-IL7-activated PROGRAMMED CELL DEATH GO - Biological Process.gmt GeneSets -2.7 0.00782 345.0 6.0 1.79
AZAvsIL7-Dn in-IL7-activated DEFENSE RESPONSE GO - Biological Process.gmt GeneSets -2.4 0.01285 125.0 3.0 0.65
AZAvsIL7-Dn in-IL7-activated NEGATIVE REGULATION OF CELLULAR PROCESS GO - Biological Process.gmt GeneSets -2.0 0.02431 469.0 6.0 2.43
AZAvsIL7-Dn in-IL7-activated REGULATION OF DEVELOPMENTAL PROCESS GO - Biological Process.gmt GeneSets -2.2 0.01786 326.0 5.0 1.69
AZAvsIL7-Dn in-IL7-activated IMMUNE RESPONSE GO - Biological Process.gmt GeneSets -2.3 0.01544 134.0 3.0 0.69
AZAvsIL7-Dn in-IL7-activated IMMUNE SYSTEM PROCESS GO - Biological Process.gmt GeneSets -2.4 0.01223 198.0 4.0 1.02
AZAvsIL7-Dn in-IL7-activated RESPONSE TO EXTERNAL STIMULUS GO - Biological Process.gmt GeneSets -2.3 0.01544 136.0 3.0 0.7
AZAvsIL7-Dn in-IL7-activated NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS GO - Biological Process.gmt GeneSets -3.0 0.00459 145.0 4.0 0.75
AZAvsIL7-Dn in-IL7-activated G PROTEIN COUPLED RECEPTOR PROTEIN SIGNALING PATHWAY GO - Biological Process.gmt GeneSets -2.6 0.00953 112.0 3.0 0.58
AZAvsIL7-Dn in-IL7-activated NEGATIVE REGULATION OF BIOLOGICAL PROCESS GO - Biological Process.gmt GeneSets -1.9 0.0271 485.0 6.0 2.51
AZAvsIL7-Dn in-IL7-activated NEGATIVE REGULATION OF PROGRAMMED CELL DEATH GO - Biological Process.gmt GeneSets -2.4 0.0125 123.0 3.0 0.64
AZAvsIL7-Dn in-IL7-activated REGULATION OF PROGRAMMED CELL DEATH GO - Biological Process.gmt GeneSets -1.8 0.02825 275.0 4.0 1.42
AZAvsIL7-Dn in-IL7-activated APOPTOSIS GO GO - Biological Process.gmt GeneSets -2.1 0.0215 344.0 5.0 1.78
AZAvsIL7-Dn in-IL7-activated INTRINSIC TO PLASMA MEMBRANE GO - Cellular Component.gmt GeneSets -2.6 0.00233 452.0 7.0 2.34
AZAvsIL7-Dn in-IL7-activated INTRINSIC TO MEMBRANE GO - Cellular Component.gmt GeneSets -2.1 0.00809 676.0 8.0 3.5
AZAvsIL7-Dn in-IL7-activated MEMBRANE PART GO - Cellular Component.gmt GeneSets -1.4 0.04302 902.0 8.0 4.67
AZAvsIL7-Dn in-IL7-activated MEMBRANE GO - Cellular Component.gmt GeneSets -1.9 0.01131 1109.0 11.0 5.74
AZAvsIL7-Dn in-IL7-activated INTEGRAL TO MEMBRANE GO - Cellular Component.gmt GeneSets -2.1 0.00744 667.0 8.0 3.45
AZAvsIL7-Dn in-IL7-activated INTEGRAL TO PLASMA MEMBRANE GO - Cellular Component.gmt GeneSets -2.7 0.00217 447.0 7.0 2.31
AZAvsIL7-Dn in-IL7-activated PLASMA MEMBRANE PART GO - Cellular Component.gmt GeneSets -2.1 0.00714 545.0 7.0 2.82
AZAvsIL7-Dn in-IL7-activated PLASMA MEMBRANE GO - Cellular Component.gmt GeneSets -3.6 2.3E-4 696.0 11.0 3.6
AZAvsIL7-Dn in-IL7-activated ENZYME ACTIVATOR ACTIVITY GO - Molecular Function.gmt GeneSets -2.9 0.00121 89.0 3.0 0.46
AZAvsIL7-Dn in-IL7-activated ENZYME REGULATOR ACTIVITY GO - Molecular Function.gmt GeneSets -1.5 0.02924 224.0 3.0 1.16
AZAvsIL7-Dn in-IL7-activated RECEPTOR ACTIVITY GO - Molecular Function.gmt GeneSets -1.9 0.01223 265.0 4.0 1.37
AZAvsIL7-Dn in-IL7-activated TRANSCRIPTION FACTOR ACTIVITY GO - Molecular Function.gmt GeneSets -1.5 0.03308 233.0 3.0 1.21
AZAvsIL7-Dn in-IL7-activated TRANSCRIPTION FACTOR BINDING GO - Molecular Function.gmt GeneSets -1.4 0.04062 249.0 3.0 1.29
AZAvsIL7-Dn in-IL7-activated CALMODULIN BINDING GO - Molecular Function.gmt GeneSets -5.6 0.0 18.0 3.0 0.09
AZAvsIL7-Dn in-IL7-activated HIV Zhou et al 2008 HIV Collection.gmt GeneSets -1.6 0.02802 221.0 3.0 1.14
AZAvsIL7-Dn in-IL7-activated GPCR downstream signaling Pathways - Reactome.gmt GeneSets -1.7 0.02002 199.0 3.0 1.03
AZAvsIL7-Dn in-IL7-activated Signal Transduction Pathways - Reactome.gmt GeneSets -3.3 5.4E-4 766.0 11.0 3.96
AZAvsIL7-Dn in-IL7-activated Signaling by GPCR Pathways - Reactome.gmt GeneSets -1.5 0.03534 238.0 3.0 1.23
AZAvsIL7-Dn in-IL7-activated Signaling by NOTCH Pathways - Reactome.gmt GeneSets -3.0 0.00111 87.0 3.0 0.45
AZAvsIL7-Dn in-IL7-activated Signaling by NOTCH1 Pathways - Reactome.gmt GeneSets -3.5 3.3E-4 63.0 3.0 0.33
AZAvsIL7-Dn in-IL7-activated V$NFKAPPAB 01 TF_miRNA Targets.gmt GeneSets -2.4 0.00899 123.0 3.0 0.64
AZAvsIL7-Dn in-IL7-activated V$CP2 01 TF_miRNA Targets.gmt GeneSets -2.3 0.00983 129.0 3.0 0.67
AZAvsIL7-Dn in-IL7-activated V$AML1 01 TF_miRNA Targets.gmt GeneSets -2.3 0.00981 128.0 3.0 0.66
AZAvsIL7-Dn in-IL7-activated V$FOXO1 01 TF_miRNA Targets.gmt GeneSets -2.6 0.0077 112.0 3.0 0.58
AZAvsIL7-Dn in-IL7-activated V$HOXA4 Q2 TF_miRNA Targets.gmt GeneSets -2.6 0.00676 106.0 3.0 0.55
AZAvsIL7-Dn in-IL7-activated V$PEA3 Q6 TF_miRNA Targets.gmt GeneSets -2.2 0.0114 141.0 3.0 0.73
AZAvsIL7-Dn in-IL7-activated V$AML1 Q6 TF_miRNA Targets.gmt GeneSets -2.3 0.00981 128.0 3.0 0.66
AZAvsIL7-Dn in-IL7-activated V$PIT1 Q6 TF_miRNA Targets.gmt GeneSets -2.9 0.00394 88.0 3.0 0.46
AZAvsIL7-Dn in-IL7-activated V$HNF4 Q6 TF_miRNA Targets.gmt GeneSets -2.5 0.00819 116.0 3.0 0.6
AZAvsIL7-Dn in-IL7-activated AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D TF_miRNA Targets.gmt GeneSets -2.2 0.01131 222.0 4.0 1.15
AZAvsIL7-Dn in-IL7-activated GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D TF_miRNA Targets.gmt GeneSets -3.6 0.00181 406.0 8.0 2.1
AZAvsIL7-Dn in-IL7-activated TGGTGCT,MIR-29A,MIR-29B,MIR-29C TF_miRNA Targets.gmt GeneSets -1.5 0.04859 345.0 4.0 1.79
AZAvsIL7-Dn in-IL7-activated TGCACTT,MIR-519C,MIR-519B,MIR-519A TF_miRNA Targets.gmt GeneSets -1.7 0.02916 295.0 4.0 1.53
AZAvsIL7-Dn in-IL7-activated CTCAGGG,MIR-125B,MIR-125A TF_miRNA Targets.gmt GeneSets -2.2 0.01239 231.0 4.0 1.2
AZAvsIL7-Dn in-IL7-activated CACTTTG,MIR-520G,MIR-520H TF_miRNA Targets.gmt GeneSets -2.9 0.00394 151.0 4.0 0.78
AZAvsIL7-Dn in-IL7-activated CTGAGCC,MIR-24 TF_miRNA Targets.gmt GeneSets -2.0 0.01586 159.0 3.0 0.82
AZAvsIL7-Dn in-IL7-activated GCAAAAA,MIR-129 TF_miRNA Targets.gmt GeneSets -2.5 0.00803 114.0 3.0 0.59
AZAvsIL7-Dn in-IL7-activated AAGCAAT,MIR-137 TF_miRNA Targets.gmt GeneSets -2.4 0.00899 123.0 3.0 0.64
AZAvsIL7-Dn in-IL7-activated AAAGACA,MIR-511 TF_miRNA Targets.gmt GeneSets -2.5 0.00837 118.0 3.0 0.61
AZAvsIL7-Dn in-IL7-activated ACTTTAT,MIR-142-5P TF_miRNA Targets.gmt GeneSets -1.7 0.03063 199.0 3.0 1.03
AZAvsIL7-Dn in-IL7-activated GTGCCAA,MIR-96 TF_miRNA Targets.gmt GeneSets -1.7 0.02951 196.0 3.0 1.01
AZAvsIL7-Dn in-IL7-activated CTTTGCA,MIR-527 TF_miRNA Targets.gmt GeneSets -2.9 0.00394 153.0 4.0 0.79
AZAvsIL7-Dn in-IL7-activated CAGCTG V$AP4 Q5 TF_miRNA Targets.gmt GeneSets -1.6 0.03349 670.0 7.0 3.47
AZAvsIL7-Dn in-IL7-activated RTAAACA V$FREAC2 01 TF_miRNA Targets.gmt GeneSets -2.0 0.0151 452.0 6.0 2.34
AZAvsIL7-Dn in-IL7-activated GGATTA V$PITX2 Q2 TF_miRNA Targets.gmt GeneSets -2.8 0.00509 243.0 5.0 1.26
AZAvsIL7-Dn in-IL7-activated hsa-miR-335-5p targets TarBase_6beta.gmt GeneSets -2.9 0.00118 1207.0 14.0 6.25
AZAvsIL7-Dn in-IL7-activated hsa-miR-375 targets TarBase_6beta.gmt GeneSets -1.4 0.03831 358.0 4.0 1.85
AZAvsIL7-Dn in-IL7-activated hsa-miR-93-5p targets TarBase_6beta.gmt GeneSets -1.6 0.02529 214.0 3.0 1.11
Download list of genes
Gene expression pattern of AZAvsIL7-Dn_in-IL7-activated
Figure: : Temporal expression patterns are displayed according to the selected conditions and comparisons. Only infected conditions are displayed, during latency as gray lines or during activation according to the color code for each drug. For individual genes, select one from the table below.
List of genes
Name Fold p p-Adj
656769 -1.8690063 6.6812746E-8 5.3003605E-5
657553 -1.2864718 8.897193E-5 0.014266743
667770 -1.1810933 3.469039E-4 0.037349157
678249 -2.6636472 3.3157921E-6 0.0012494734
768957 -1.9542443 3.070219E-8 2.8923383E-5
65796572 -0.7711941 4.998329E-4 0.04750323
65836650 -1.107831 2.1403727E-8 2.150789E-5
67668855 -0.7462712 1.1585963E-4 0.016954875
68848852 -2.5477583 2.93654E-12 1.1065617E-8
70777849 -1.1399245 1.2613917E-4 0.017906377
73765052 -1.3926042 2.229239E-11 4.8001887E-8
79689049 -1.7706094 4.1345807E-4 0.041735604
80658375 -1.23187 3.4905747E-6 0.0012832545
80767680 -1.411736 6.082446E-11 1.0186745E-7
82718349 -0.74202466 1.7269296E-4 0.02205933
82718350 -0.71278995 5.0109555E-4 0.04750323
83718372 -0.7610523 9.817233E-5 0.015099505
84728265 -0.71554774 3.1458537E-4 0.03461128
6566846649 -0.9666304 5.28091E-5 0.009827057
6582658051 -0.8143695 2.6484244E-4 0.030707462
6767787150 -0.88739526 1.2936586E-5 0.0036109844
6780786955 -1.1513809 6.002669E-7 2.9769356E-4
6865807550 -1.0395671 4.8425398E-4 0.04678949
6977825280 -0.89890176 2.820734E-5 0.0065330337
6980726552 -1.1360825 2.5947907E-4 0.030318823
6986735066 -0.7902287 4.2742577E-5 0.008366998
7065737751 -1.4438978 2.5568436E-13 1.2846435E-9
7067716680 -1.9739124 4.7628674E-8 4.222982E-5
7082658449 -0.72929806 2.994356E-4 0.033682037
7088896855 -0.8246358 3.5269719E-4 0.03770358
7180655151 -2.0772595 2.1207363E-6 8.1963744E-4
7268656753 -0.9093755 3.8761523E-6 0.0013910772
7367657752 -0.9172944 7.9716236E-5 0.013203987
7765777650 -0.7364801 1.7975834E-4 0.022768887
7777805052 -0.85529774 3.3155455E-5 0.007349297
7869767650 -1.1503408 3.7008533E-5 0.0075382376
7885657550 -1.2378049 1.306073E-9 1.6405365E-6
8065847650 -0.7296805 1.9934456E-4 0.024591668
8378696849 -0.8858449 1.2019739E-5 0.0035524222
8379827649 -0.80181175 3.2081552E-5 0.007217392
8673808249 -1.5827816 8.2781764E-5 0.013416876
8980697651 -1.0011537 1.8439694E-5 0.004556418
8980697652 -1.6722912 1.1669221E-11 2.9315029E-8
657773676549 -0.8694419 6.7794836E-6 0.002128899
657773717950 -0.69741863 4.5977236E-4 0.045268543
706688795150 -0.69707847 3.3138538E-4 0.035935048
737170768249 -0.74339765 1.4521746E-4 0.019200552
738067697049 -0.7639453 2.4279483E-4 0.028816113
806688738049 -0.6922899 3.276168E-4 0.035783827
807688686749 -1.0450332 2.8606131E-5 0.0065330337
807880766555 -0.82827604 3.5589725E-5 0.0073585347
837665777054 -0.7148701 2.2684992E-4 0.027354471
837987657268 -1.0461009 2.8593472E-4 0.032650713
838271658051 -0.8596529 1.272632E-4 0.017906377
77846982706850 -0.78377086 5.644124E-5 0.010249865
80737551738049 -1.0287243 1.18702154E-7 8.525414E-5
84678049497650 -1.0502583 1.494116E-6 6.2557805E-4
84787065738051 -1.0147161 1.9121042E-7 1.2530934E-4
84826586564551 -0.7861162 1.4805062E-4 0.019299423
84836750506851 -0.97183704 3.8513168E-5 0.0077401195
90708051547650 -0.7940384 3.9317358E-5 0.00779777
6765766779677949 -0.6710425 5.1224895E-4 0.047957316
7765826775837649 -0.70706004 4.8317437E-4 0.04678949
8480535173788049 -0.7495096 1.1433572E-4 0.016954875
674955111114102494851 -1.0815965 2.1342811E-7 1.3404175E-4
65674849485551494650 -1.5992762 1.4306948E-4 0.019177016
65674857515452504652 -0.85361063 2.499499E-4 0.029433554
65764951515253564649 -0.75099015 2.3928154E-4 0.028624527
65765357505056524650 -0.8030888 5.749999E-5 0.010317826
678467455155567250504650 -0.80533 4.0542503E-4 0.041571233
678468455053484966564649 -1.6322504 6.1751234E-6 0.0019803753
828049494550555576504651 -0.9300385 9.349832E-5 0.01468021
828049494551535473504652 -0.9481012 7.09522E-5 0.012039275
828049494552535370534650 -1.1188273 8.2769715E-5 0.013416876
828049494556515065524653 -1.31228 2.6679302E-7 1.5427328E-4
828052455552506749574656 -0.8248555 5.6230605E-5 0.010249865
828053455757537449504650 -1.0354393 6.2128623E-7 2.9769356E-4
82804949454951497250524652 -1.1079211 7.828726E-6 0.0023600475